Material Safety Data Sheet
Tetramethylammonium hydroxide solutions

ACC# 23082
Section 1 - Chemical Product and Company Identification

MSDS Name: Tetramethylammonium hydroxide solutions
Catalog Numbers: O4642-100, O4643-100
Synonyms:
N,N,N-Trimethylmethanaminium hydroxide.
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
7732-18-5 Water 75-90 231-791-2
75-59-2 Tetramethylammonium hydroxide 10-25 200-882-9

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: colorless liquid.
Danger! Causes eye and skin burns. May cause severe respiratory tract irritation with possible burns. May cause severe digestive tract irritation with possible burns. May cause central nervous system depression.
Target Organs: Central nervous system.


Potential Health Effects
Eye: Causes eye burns.
Skin: Causes skin burns. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
Ingestion: May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause central nervous system depression.
Inhalation: May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. Causes chemical burns to the respiratory tract. Exposure produces central nervous system depression. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
Chronic: Prolonged or repeated skin contact may cause dermatitis.

Section 4 - First Aid Measures


Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Use extinguishing media appropriate to the surrounding fire. Substance is noncombustible. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Contact with metals may evolve flammable hydrogen gas.
Extinguishing Media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 0; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation. Do not get water inside containers.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale. Use with adequate ventilation. Discard contaminated shoes.
Storage: Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store in metal containers.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Water none listed none listed none listed
Tetramethylammonium hydroxide none listed none listed none listed

OSHA Vacated PELs: Water: No OSHA Vacated PELs are listed for this chemical. Tetramethylammonium hydroxide: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear yellow - colorless
Odor: Ammonia-like odor.
pH: Not available.
Vapor Pressure: 17.5 mm Hg @ 20
Vapor Density: 3.14
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 110 deg C @ 760.00mm Hg
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: soluble in water
Specific Gravity/Density:1.0200g/cm3
Molecular Formula:C4H13NO
Molecular Weight:91.15

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures. Absorbs carbon dioxide from the air.
Conditions to Avoid: Incompatible materials, metals, excess heat, strong acids, oxidizers, temperatures above 75C (167F).
Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, alkali metals, aluminum, halogens, acid anhydrides, acid chlorides.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen, ammonia, amines, methanol.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information


RTECS#:      
CAS# 7732-18-5: ZC0110000      
CAS# 75-59-2: PA0875000
LD50/LC50:
CAS# 7732-18-5:
     Oral, rat: LD50 = >90 mL/kg;
CAS# 75-59-2:
     Dermal, guinea pig: LD50 = 25 mg/kg;
Carcinogenicity:
CAS# 7732-18-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 75-59-2: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: See actual entry in RTECS for complete information.

Section 12 - Ecological Information


Ecotoxicity: No data available. No information available.
Environmental: Terrestrial: Completely soluble in water therefore it is likely to leach.
Physical: No information available.
Other: No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: TETRAMETHYLAMMONIUM HYDROXIDE TETRAMETHYLAMMONIUM HYDROXIDE
Hazard Class: 8 8
UN Number: UN1835 UN1835
Packing Group: II II

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 7732-18-5 is listed on the TSCA inventory.
     CAS# 75-59-2 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 75-59-2: acute.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
     CAS# 75-59-2 can be found on the following state right to know lists: New Jersey.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     C
Risk Phrases:

     R 34 Causes burns.

Safety Phrases:

     S 25 Avoid contact with eyes.
     S 36/37/39 Wear suitable protective clothing, gloves and eye/face
     protection.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).

WGK (Water Danger/Protection)

     CAS# 7732-18-5: No information available.
     CAS# 75-59-2: No information available.
Canada - DSL/NDSL
     CAS# 7732-18-5 is listed on Canada's DSL List.
     CAS# 75-59-2 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of E.
Canadian Ingredient Disclosure List
     CAS# 75-59-2 is listed on the Canadian Ingredient Disclosure List.

Section 16 - Additional Information

MSDS Creation Date: 4/01/1999
Revision #4 Date: 7/29/2004

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.